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Steroid Prescriptions
One of the most misunderstood class of drugs in medicine is a group
known as steroids. It is easily confusing because actually steroids are
a group of different hormones that are naturally produced by the body.
Within this group are several different types that have very different
functions, which depend on slight changes in the chemical structure of
the steroid hormone.
Almost everyone knows that some body builders take steroids to increase
their muscle size. What they are taking is actually some variation of
the male hormone testosterone. Estrogen and progesterone are examples of
female steroid hormones, a great example of how different their effects
can be.
The steroid group most commonly prescribed, however, is an entirely
different group which includes cortisone. The cortisone group includes
brand name drugs like Predisone, Decadron, Celestone and many others.
Almost all of the most commonly used nasal sprays for allergy fall into
this group as well, including Flonase, Nasonex, Rhinocort etc. (They all
work about the same). When doctors mention steroids, they are almost
always referring to drugs in the cortisone group.
It is important to understand this group because they are very commonly
used and because they can have some serious side effects which mostly
depend on how much is taken and for how long. The reason this cortisone
type of drug is prescribed so often is because it works incredibly well
to reduce unwanted reactions by the body’s immune system. It is the
action of the immune system’s various cells and chemicals that causes
allergy, asthma, arthritis, and many other inflammatory conditions
throughout the body. Virtually nothing is more powerful or works better
than steroids to counteract the immune system when it creates these
unwanted conditions. But cortisone drugs also can have unwanted side
effects that increase with dosage and duration of treatment.
The inhaled nasal steroids for allergy like Flonase have been
extensively tested and because they are not significantly absorbed are
very safe even when used everyday. Short courses of steroids for less
than two weeks, which include injections, mainly risk making preexisting
conditions worse. Because cortisone type drugs increase blood sugar
significantly, diabetics should try to avoid them. Steroids increase the
risk of stomach ulcers (especially when given with aspirin-type drugs),
can worsen glaucoma and raise blood pressure. Common side effects
include increased appetite, fluid retention, facial flushing, insomnia,
weight gain, and just feeling good. Very rare complications of
short-term use include tissue death of the hipbone requiring hip
replacement and temporary psychosis. Longer-term use beyond two weeks
involves too many serious complications to discuss here.
Steroids are wonderful for many conditions affecting the ears, nose, and
throat because they reduce swelling in areas where swelling leads to
complications. They also help pain by reducing inflammation.
Unfortunately, they do not help viral infections and may prolong viral
shedding. While they are wonderful for asthma and allergy, frequent
shots or pills should be reserved for more severe cases.
Whenever your doctor or nurse prescribes a steroid, you should make sure
they know your complete medical history and follow their directions
precisely. That way, you will get maximum benefit while minimizing any
risks. And, as with any medication, if you are experiencing unexplained
side effects, let your doctor know about it.
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